Lab Notes.
Long-form notes on the actives, formulas, and methodology behind clinical-grade personalized skincare — straight from the Mxt lab.

Why Stacking Actives Beats Layering Products.
Most routines deliver four or five actives across seven products. Here's the math on why fewer products at clinical doses outperform pile...

A Field Guide To The Retinoid Family.
Retinol, retinaldehyde, tretinoin, adapalene, granactive — six molecules in one family, conversion rates that matter, and how to choose b...

What Adult Acne Is Actually Telling You.
Hormones, barrier damage, occlusion, microbiome — most adult acne has a cause that responds to a specific intervention. The trick is read...

Sunscreen Filters, Compared: An Evidence Review.
Mineral, organic, hybrid, next-gen — what the photostability data actually shows, where the regulatory gaps are, and why the US lags the ...

Why We Don't Use Fragrance In A Single Mxt Formula.
A short note on a long-standing decision — and what the sensitization data actually says about parfum in leave-on products.

Vitamin C: Stable Enough To Bother With?
L-ascorbic acid, ethyl ascorbic acid, ascorbyl glucoside, MAP — a head-to-head on stability, penetration, and which delivery vehicle is w...
Get A Routine From A Formulary Of 200+ Clinically Validated Actives.
A 5-minute diagnostic. No quizzes that send everyone the same three products. Just the actives your skin actually needs, at clinical doses.
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Purging Vs. Breaking Out: How To Tell, And When To Stop.
A practical framework for evaluating whether your skin is adjusting to a new active or rejecting it — and the timeline that actually matt...

What Tretinoin Actually Does, Over 12 Weeks.
A week-by-week look at how tretinoin remodels the skin barrier — what's happening biologically, what you'll see in the mirror, and why mo...


